Moieties of Pneumococcal Teichoic Acid Human L-Ficolin Recognizes Phosphocholine
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Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic acid.
Human L-ficolin is a soluble protein of the innate immune system able to sense pathogens through its fibrinogen (FBG) recognition domains and to trigger activation of the lectin complement pathway through associated serine proteases. L-Ficolin has been previously shown to recognize pneumococcal clinical isolates, but its ligands and especially its molecular specificity remain to be identified. ...
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